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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPRU All Species: 21.21
Human Site: T867 Identified Species: 51.85
UniProt: Q92729 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92729 NP_005695.3 1446 162423 T867 R K G S P Y H T G Q L H P A V
Chimpanzee Pan troglodytes XP_513263 1483 166127 T904 R K G S P Y H T G Q L H P A V
Rhesus Macaque Macaca mulatta XP_001115805 1350 152055 G797 M K T A E G Y G F K Q E Y E S
Dog Lupus familis XP_852271 1446 162532 T867 R K G S P Y H T G Q L H P A V
Cat Felis silvestris
Mouse Mus musculus B1AUH1 1446 162475 T867 R K G S P Y H T G Q L H P A V
Rat Rattus norvegicus Q64604 1898 211475 G1316 R L N Y Q T P G M R D H P P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q6YI48 1434 161661 T856 R K G S P Y H T G Q L H P A V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B3DK56 1444 162642 G867 K G S P Y H T G Q L H P A V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16621 2029 229038 T1263 K I P D Q F L T D D L L P G R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9BMN8 2200 246601 T1620 P N N G N N M T T V S H P A V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.6 92.6 97 N.A. 95.3 25.6 N.A. N.A. 84.9 N.A. 75.1 N.A. 24.5 N.A. 23.4 N.A.
Protein Similarity: 100 96.7 92.8 98.5 N.A. 97.3 41.6 N.A. N.A. 92.5 N.A. 85.8 N.A. 41 N.A. 36.8 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 20 N.A. N.A. 100 N.A. 0 N.A. 20 N.A. 33.3 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 33.3 N.A. N.A. 100 N.A. 13.3 N.A. 33.3 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 10 60 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 10 10 10 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 10 0 10 0 % E
% Phe: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 10 50 10 0 10 0 30 50 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 10 50 0 0 0 10 70 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 20 60 0 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 10 0 0 10 60 10 0 0 0 % L
% Met: 10 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % M
% Asn: 0 10 20 0 10 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 10 10 50 0 10 0 0 0 0 10 80 10 0 % P
% Gln: 0 0 0 0 20 0 0 0 10 50 10 0 0 0 0 % Q
% Arg: 60 0 0 0 0 0 0 0 0 10 0 0 0 0 20 % R
% Ser: 0 0 10 50 0 0 0 0 0 0 10 0 0 0 10 % S
% Thr: 0 0 10 0 0 10 10 70 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 60 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 10 50 10 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _